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QuickView for PDP2;jsessionid=F4C76F25907D3E6539736709FFBA13C5 (gene)


Gene Symbol:
PDP2 Homo sapiens Homo sapiens
Full name:
pyruvate dehyrogenase phosphatase catalytic subunit 2
Synonyms:
PDPC 2, PPM2B, PPM2C2, [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial, pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial, protein phosphatase 2C, magnesium-dependent, catalytic subunit 2, protein phosphatase, Mg2+/Mn2+ dependent 2B, pyruvate dehydrogenase phosphatase isoenzyme 2
Genomic Location:
Chr 16: 65471937-65479356
Description:
This gene is a mitochondrial protein that functions as a phosphatase and is involved in the enzymatic resetting of the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants encoding the same protein.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 16
16q22.1





GO Molecular Function

protein serine/threonine phosphatase activity | cation binding | phosphatase activity | hydrolase activity | catalytic activity | phosphoprotein phosphatase activity | hydrolase activity, acting on ester bonds | ion binding | phosphoric ester hydrolase activity | metal ion binding | [pyruvate dehydrogenase (lipoamide)] phosphatase activity

GO Biological Process

protein serine/threonine phosphatase activity | protein dephosphorylation | cellular process | regulation of cellular process | regulation of metabolic process | phosphatase activity | protein modification process | macromolecule modification | nitrogen compound metabolic process | phosphorus metabolic process | phosphoprotein phosphatase activity | regulation of nitrogen compound metabolic process | regulation of fatty acid metabolic process | phosphate-containing compound metabolic process | regulation of cellular metabolic process | protein metabolic process | regulation of acetyl-CoA biosynthetic process from pyruvate | metabolic process | organic substance metabolic process | regulation of phosphate metabolic process | regulation of acyl-CoA biosynthetic process | dephosphorylation | cellular protein metabolic process | regulation of cellular ketone metabolic process | cellular protein modification process | regulation of lipid metabolic process | cellular metabolic process | macromolecule metabolic process | [pyruvate dehydrogenase (lipoamide)] phosphatase activity | regulation of phosphorus metabolic process

GO Cellular Component

mitochondrial matrix | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | membrane-enclosed lumen | intracellular