QuickView for PELP1 (gene)

Gene Symbol:

PELP1 Homo sapiens

Full name:

proline, glutamate and leucine rich protein 1

Synonyms:

MNAR, P160, proline-, glutamic acid- and leucine-rich protein 1, modulator of non-genomic activity of estrogen receptor, proline and glutamic acid rich nuclear protein, transcription factor HMX3

Genomic Location:

Chr 17: 4521428-4554381

Description:

This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of se...

View Full Description

This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CMYB_01 ,  YRTCANNRCGC_UNKNOWN ,  CREB_Q3 ,  GGGAGGRR_MAZ_Q6 ,  CREB_02 ,  TGCCAAR_NF1_Q6 ,  OCT1_06 ,  E2F1_Q3 ,  E2F_Q3 ,  E2F_Q3_01

Cytogenetic Map:

17p13.2

search → result