Correlation Engine 2.0
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QuickView for PGD (gene)

Gene Symbol:
PGD Homo sapiens Homo sapiens
Full name:
phosphogluconate dehydrogenase
6PGD, 6-phosphogluconate dehydrogenase, decarboxylating
Genomic Location:
Chr 1: 10381672-10402788
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two e...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 1

Transcripts Names
Protein Names

GO Molecular Function

oxidoreductase activity, acting on CH-OH group of donors | NADP binding | cofactor binding | nucleotide binding | coenzyme binding | catalytic activity | organic cyclic compound binding | phosphogluconate dehydrogenase (decarboxylating) activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | heterocyclic compound binding | oxidoreductase activity | small molecule binding

GO Biological Process

oxidoreductase activity, acting on CH-OH group of donors | cellular process | nucleotide metabolic process | ribose phosphate metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | monocarboxylic acid metabolic process | pentose-phosphate shunt | cellular nitrogen compound metabolic process | pentose biosynthetic process | cofactor metabolic process | nitrogen compound metabolic process | phosphorus metabolic process | organophosphate metabolic process | monosaccharide metabolic process | small molecule metabolic process | cellular carbohydrate metabolic process | nucleobase-containing small molecule metabolic process | carbohydrate biosynthetic process | biosynthetic process | carbohydrate metabolic process | D-gluconate metabolic process | phosphate-containing compound metabolic process | glyceraldehyde-3-phosphate metabolic process | pentose-phosphate shunt, oxidative branch | carboxylic acid metabolic process | cellular aldehyde metabolic process | phosphogluconate dehydrogenase (decarboxylating) activity | metabolic process | oxidation-reduction process | nucleobase-containing compound metabolic process | organic substance metabolic process | glucose 6-phosphate metabolic process | organic acid metabolic process | NADP metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | nicotinamide nucleotide metabolic process | carbohydrate derivative metabolic process | heterocycle metabolic process | pentose metabolic process | cellular metabolic process | oxidoreductase activity

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cytosol | intracellular