QuickView for PH1 (gene)

Gene Symbol:

AGXT Homo sapiens

Full name:

alanine-glyoxylate aminotransferase

Synonyms:

AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6, serine--pyruvate aminotransferase, L-alanine: glyoxylate aminotransferase 1, hepatic peroxisomal alanine:glyoxylate aminotransferase

Genomic Location:

Chr 2: 241456835-241467210

Description:

This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.

This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Gallus gallus ,  Bos taurus

External Links:

Entrez Gene

Cytogenetic Map:

2q37.3

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