QuickView for PHB2 (gene)
- Gene Symbol:
- PHB2
Homo sapiens - Full name:
- prohibitin 2
- Synonyms:
- BAP, BCAP37, Bap37, PNAS-141, REA, hBAP, p22, prohibitin-2, B-cell associated protein, B-cell receptor-associated protein BAP37, D-prohibitin, repressor of estrogen receptor activity
- Genomic Location:
- Chr 12: 6944778-6950152
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
12p13.31
GO Molecular Function
hormone receptor binding | estrogen receptor binding | signaling receptor binding | protein N-terminus binding | amide binding | nuclear hormone receptor binding | protein binding | transcription factor binding | steroid hormone receptor binding | protein C-terminus binding
GO Biological Process
RNA metabolic process | regulation of ERK1 and ERK2 cascade | regulation of cell cycle process | cellular response to decreased oxygen levels | positive regulation of cellular component organization | developmental process involved in reproduction | protein stabilization | regulation of cell cycle G1/S phase transition | mammary gland duct morphogenesis | morphogenesis of an epithelium | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | establishment of localization | regulation of immune system process | negative regulation of cellular process | negative regulation of RNA biosynthetic process | response to metal ion | positive regulation of phosphate metabolic process | regulation of organelle organization | intracellular transport | cellular process | localization | epithelial tube morphogenesis | protein transport | regulation of exit from mitosis | negative regulation of signaling | metal ion transport | regulation of mitotic nuclear division | negative regulation of nucleic acid-templated transcription | macromolecule localization | mitochondrial calcium ion transmembrane transport | negative regulation of apoptotic process | response to hypoxia | regulation of proteolysis | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | response to inorganic substance | establishment of localization in cell | negative regulation of cellular metabolic process | tissue development | cellular response to retinoic acid | regulation of immune response | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | protein import into nucleus | positive regulation of cell cycle phase transition | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | cellular component organization | cellular response to metal ion | mammary gland morphogenesis | response to stimulus | regulation of mitotic cell cycle phase transition | chromosome segregation | positive regulation of protein metabolic process | cellular response to hypoxia | gland morphogenesis | response to stress | intracellular protein transport | regulation of intracellular steroid hormone receptor signaling pathway | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | regulation of mammary gland epithelial cell proliferation | tube morphogenesis | protein localization to nucleus | regulation of cell cycle phase transition | regulation of humoral immune response | reproduction | cellular response to inorganic substance | cellular localization | divalent metal ion transport | cellular nitrogen compound metabolic process | negative regulation of metabolic process | regulation of protein processing | cellular biosynthetic process | mitochondrion organization | regulation of morphogenesis of a branching structure | regulation of nucleic acid-templated transcription | system development | response to oxygen levels | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of organelle organization | regulation of protein stability | multicellular organism development | calcium ion transmembrane transport | regulation of MAPK cascade | sister chromatid segregation | mammary gland development | protein import into nucleus, translocation | regulation of intracellular estrogen receptor signaling pathway | regulation of phosphorylation | ion transmembrane transport | regulation of acute inflammatory response | positive regulation of cell cycle | mammary gland lobule development | positive regulation of mitotic cell cycle | regulation of gene expression | organic substance transport | cellular response to stress | response to lipid | cell cycle | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | peptide transport | negative regulation of DNA-binding transcription factor activity | positive regulation of intracellular signal transduction | protein localization to organelle | import into nucleus | negative regulation of mammary gland epithelial cell proliferation | negative regulation of intracellular steroid hormone receptor signaling pathway | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | regulation of complement activation | positive regulation of cell cycle G1/S phase transition | protein import | nuclear chromosome segregation | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | regulation of RNA metabolic process | response to retinoic acid | negative regulation of intracellular estrogen receptor signaling pathway | regulation of mitotic cell cycle | positive regulation of molecular function | cation transmembrane transport | negative regulation of epithelial cell proliferation | positive regulation of protein modification process | cellular response to calcium ion | response to organic substance | gland development | tissue morphogenesis | branching morphogenesis of an epithelial tube | response to wounding | regulation of animal organ morphogenesis | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | establishment of protein localization to organelle | anatomical structure development | positive regulation of mitotic cell cycle phase transition | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | development of secondary sexual characteristics | cellular protein localization | amide transport | calcium ion transport | development of secondary female sexual characteristics | nucleobase-containing compound metabolic process | organic substance metabolic process | nuclear transport | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | mammary gland branching involved in thelarche | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | inorganic cation transmembrane transport | mammary gland epithelium development | establishment of protein localization | transcription, DNA-templated | positive regulation of exit from mitosis | positive regulation of MAPK cascade | morphogenesis of a branching epithelium | mammary gland alveolus development | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | transmembrane transport | regulation of transcription, DNA-templated | protein localization | regulation of epithelial cell proliferation | positive regulation of phosphorylation | morphogenesis of a branching structure | anatomical structure morphogenesis | cation transport | cellular macromolecule localization | cellular macromolecule biosynthetic process | nucleocytoplasmic transport | regulation of developmental process | developmental process | organelle organization | positive regulation of cell cycle process | sister chromatid cohesion | tube development | negative regulation of cell proliferation | heterocycle metabolic process | response to calcium ion | positive regulation of metabolic process | chromosome organization | regulation of branching involved in mammary gland duct morphogenesis | ion transport | cellular metabolic process | cellular response to organic substance | regulation of cell death | negative regulation of cell death | regulation of inflammatory response | branching involved in mammary gland duct morphogenesis | regulation of cellular component organization | positive regulation of signaling | positive regulation of mitotic nuclear division | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | neuron projection | organelle membrane | cell | organelle outer membrane | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | cell projection | mitochondrion | membrane-bounded organelle | nucleus | organelle | mitochondrial outer membrane | mitochondrial envelope | cell periphery | axon | membrane-enclosed lumen | outer membrane | nuclear matrix | mitochondrial membrane | cell surface | intracellular | membrane | nuclear periphery
