QuickView for PLA2G7 (gene)

Gene Symbol:

PLA2G7 Homo sapiens

Full name:

phospholipase A2 group VII

Synonyms:

LDL-PLA2, LP-PLA2, PAFAD, PAFAH, platelet-activating factor acetylhydrolase, 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, LDL-PLA(2), LDL-associated phospholipase A2, PAF 2-acylhydrolase, PAF acetylhydrolase, gVIIA-PLA2, group-VIIA phospholipase A2, lipoprotein-associated phospholipase A2, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

Genomic Location:

Chr 6: 46780237-46811061

Description:

The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.

The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

WTGAAAT_UNKNOWN ,  GGGAGGRR_MAZ_Q6

Cytogenetic Map:

6p12.3

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