QuickView for PLCbeta1 (gene)
- Gene Symbol:
- Plcb1
Rattus norvegicus - Full name:
- phospholipase C beta 1
- Synonyms:
- PLC'1, PLCbeta1, Phosphb, RATPHOSPHB, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1, PLC-154, PLC-I, PLC-beta-1, Phospholipase C-beta1, phosphoinositide phospholipase C, phosphoinositide phospholipase C-beta-1, phospholipase C, beta 1 (phosphoinositide-specific), phospholipase C-I
- Genomic Location:
- Chr 3: 122797846-123525301
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
E47_01 , AACTTT_UNKNOWN , SOX5_01 , E4BP4_01 , TAL1BETAE47_01 , TAL1ALPHAE47_01 , TAL1BETAITF2_01 , CEBPB_01 , HNF3B_01 , MYOD_Q6
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-125 , Predicted Gene Targets for miR-130 , Predicted Gene Targets for miR-153 , Predicted Gene Targets for miR-19 , Predicted Gene Targets for miR-20 , Predicted Gene Targets for miR-205 , Predicted Gene Targets for miR-26 , Predicted Gene Targets for miR-328 , Predicted Gene Targets for miR-330 , Predicted Gene Targets for miR-34
GO Molecular Function
enzyme activator activity | phosphatidylinositol-4,5-bisphosphate binding | cation binding | phospholipase activity | GTPase activator activity | enzyme binding | lipid binding | GTPase regulator activity | hydrolase activity | phospholipid binding | molecular function regulator | catalytic activity | anion binding | phosphatidylinositol bisphosphate binding | hydrolase activity, acting on ester bonds | identical protein binding | ion binding | lipase activity | protein binding | protein homodimerization activity | protein dimerization activity | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | lamin binding | phosphatidylinositol binding | phosphatidylinositol phospholipase C activity | calcium ion binding | enzyme regulator activity | phospholipase C activity | calmodulin binding | metal ion binding | phosphatidylinositol phosphate binding
GO Biological Process
egg activation | positive regulation of acrosome reaction | brain development | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | negative regulation of immune system process | response to cytokine | response to interleukin-1 | positive regulation of cellular component organization | intracellular signal transduction | enzyme activator activity | regulation of localization | regulation of cell cycle G1/S phase transition | positive regulation of embryonic development | positive regulation of G1/S transition of mitotic cell cycle | phosphatidylinositol metabolic process | regulation of meiotic cell cycle | regulation of immune system process | response to hormone | negative regulation of cellular process | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | nervous system development | response to drug | organophosphate catabolic process | regulation of G1/S transition of mitotic cell cycle | polyol metabolic process | positive regulation of phosphate metabolic process | regulation of organelle organization | cellular response to ether | phospholipid metabolic process | positive regulation of GTPase activity | positive regulation of cellular biosynthetic process | cellular process | positive regulation of glycoprotein biosynthetic process | organic substance catabolic process | regulation of cell motility | acetylcholine receptor signaling pathway | activation of meiosis involved in egg activation | regulation of embryonic development | negative regulation of nucleic acid-templated transcription | GTPase activator activity | learning | phosphatidylinositol catabolic process | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | response to inorganic substance | negative regulation of cellular metabolic process | response to peptide hormone | negative regulation of monocyte extravasation | regulation of cell differentiation | negative regulation of cell motility | regulation of cellular process | cellular response to lipid | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | catabolic process | regulation of cellular extravasation | positive regulation of cell cycle phase transition | response to ether | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | insulin-like growth factor receptor signaling pathway | cellular lipid metabolic process | head development | positive regulation of stress-activated protein kinase signaling cascade | regulation of acrosome reaction | response to stimulus | regulation of glycoprotein biosynthetic process | regulation of mitotic cell cycle phase transition | positive regulation of protein metabolic process | GTPase regulator activity | glycerophospholipid catabolic process | alcohol metabolic process | response to peptide | regulation of cell cycle phase transition | reproduction | positive regulation of myoblast differentiation | cellular response to organic cyclic compound | G-protein coupled receptor signaling pathway | positive regulation of meiotic cell cycle | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular response to glyceraldehyde | response to interleukin-12 | interleukin-12-mediated signaling pathway | molecular function regulator | positive regulation of CD24 biosynthetic process | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | organic hydroxy compound metabolic process | regulation of fertilization | response to nitrogen compound | cellular response to hormone stimulus | negative regulation of cellular extravasation | system development | reproductive process | regulation of signal transduction | positive regulation of organelle organization | multicellular organism development | cellular response to peptide hormone stimulus | regulation of MAPK cascade | phosphorus metabolic process | G-protein coupled acetylcholine receptor signaling pathway | learning or memory | response to fatty acid | regulation of catalytic activity | lipid metabolic process | regulation of phosphorylation | cellular response to ammonium ion | telencephalon development | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of gene expression | response to lipid | nervous system process | cellular response to peptide | cellular response to vasopressin | cell cycle | organophosphate metabolic process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | response to ammonium ion | response to acetylcholine | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | positive regulation of JNK cascade | interleukin-1-mediated signaling pathway | small molecule metabolic process | positive regulation of interleukin-12 production | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | regulation of cellular component movement | phospholipid catabolic process | fat cell differentiation | positive regulation of hydrolase activity | positive regulation of cell differentiation | cognition | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | G2/M transition of mitotic cell cycle | fertilization | regulation of GTPase activity | mitotic cell cycle phase transition | positive regulation of cell cycle G1/S phase transition | regulation of leukocyte migration | phosphate-containing compound metabolic process | cellular response to drug | cell communication | regulation of cellular metabolic process | cellular lipid catabolic process | regulation of protein metabolic process | positive regulation of signal transduction | cell cycle G2/M phase transition | response to monosaccharide | regulation of protein phosphorylation | regulation of locomotion | glycerolipid metabolic process | regulation of RNA metabolic process | cerebral cortex development | positive regulation of meiotic nuclear division | cellular response to fatty acid | single fertilization | regulation of mitotic cell cycle | positive regulation of molecular function | interleukin-15-mediated signaling pathway | cellular response to fluoride | response to interleukin-15 | positive regulation of protein modification process | regulation of growth | activation of meiosis | response to organic substance | regulation of meiotic nuclear division | inositol trisphosphate metabolic process | regulation of intracellular signal transduction | anatomical structure development | positive regulation of mitotic cell cycle phase transition | mitotic cell cycle | cell surface receptor signaling pathway | response to vasopressin | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | regulation of myoblast differentiation | cellular response to carbohydrate stimulus | behavior | cellular response to ionomycin | lipid catabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | forebrain development | pallium development | negative regulation of cellular component movement | regulation of phosphate metabolic process | positive regulation of fertilization | positive regulation of glycoprotein metabolic process | positive regulation of cytokine production | regulation of JNK cascade | cell activation | positive regulation of MAPK cascade | memory | regulation of stress-activated MAPK cascade | regulation of cell communication | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of developmental growth | positive regulation of phosphorylation | enzyme regulator activity | regulation of cytokine production | glutamate receptor signaling pathway | negative regulation of leukocyte migration | regulation of developmental process | glycerophospholipid metabolic process | regulation of G-protein coupled receptor protein signaling pathway | developmental process | cellular response to interleukin-1 | positive regulation of cell cycle process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | cell cycle phase transition | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | response to fluoride | cellular metabolic process | cellular response to organic substance | response to carbohydrate | negative regulation of locomotion | sexual reproduction | regulation of cellular component organization | positive regulation of signaling | inositol phosphate metabolic process | signal transduction | regulation of signaling | positive regulation of gene expression | negative regulation of mononuclear cell migration | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | endomembrane system | nucleoplasm | nuclear envelope | chromatin | nuclear chromosome | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | cytosol | intracellular | myelin sheath | membrane
