QuickView for PLXNA3;jsessionid=04831900403B76FA06C6884E4B7B2B85 (gene)

Gene Symbol:

PLXNA3 Homo sapiens

Full name:

plexin A3

Synonyms:

6.3, HSSEXGENE, PLXN3, PLXN4, XAP-6, plexin-A3, Sex chromosome X transmembrane protein of HGF receptor family 3, plexin-4, semaphorin receptor SEX

Genomic Location:

Chr X: 153339817-153355179

Description:

This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor p...

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This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGNNNNNNKCCAR_UNKNOWN ,  CDPCR3HD_01 ,  TAL1BETAE47_01 ,  GGGYGTGNY_UNKNOWN ,  ZID_01 ,  TGCCTTA_MIR124A ,  CDPCR1_01 ,  GTGCCTT_MIR506 ,  CP2_02 ,  CTTTGT_LEF1_Q2

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-137

Cytogenetic Map:

Xq28

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