QuickView for POLE2;jsessionid=0C05DE75AF4E6A060BCF4D6236FA2C68 (gene)

Gene Symbol:

POLE2 Homo sapiens

Full name:

DNA polymerase epsilon 2, accessory subunit

Synonyms:

DPE2, DNA polymerase epsilon subunit 2, DNA polymerase II subunit 2, DNA polymerase epsilon subunit B, polymerase (DNA directed), epsilon 2 (p59 subunit), polymerase (DNA directed), epsilon 2, accessory subunit, polymerase (DNA) epsilon 2, accessory subunit

Genomic Location:

Chr 14: 49180028-49224685

Description:

DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency.

DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E2F1_Q4_01 ,  E2F4DP1_01 ,  E2F_Q6_01 ,  STAT6_01 ,  E2F1_Q4 ,  E2F_Q6 ,  E2F1_Q6_01 ,  E2F_Q4 ,  GGGCGGR_SP1_Q6 ,  STAT5A_03 ,  E2F1DP2_01 ,  YKACATTT_UNKNOWN ,  S8_01 ,  YCATTAA_UNKNOWN ,  E2F1DP1_01 ,  E2F_Q4_01 ,  E2F1DP1RB_01 ,  E2F_02 ,  E2F1_Q3 ,  E2F4DP2_01 ,  E2F_Q3 ,  TGACATY_UNKNOWN ,  E2F_Q3_01 ,  E2F1_Q6 ,  SGCGSSAAA_E2F1DP2_01

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Cytogenetic Map:

14q21.3

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