QuickView for POLR1C (gene)

Gene Symbol:

POLR1C Homo sapiens

Full name:

RNA polymerase I subunit C

Synonyms:

AC40, HLD11, RPA39, RPA40, RPA5, RPAC1, RPC40, TCS3, DNA-directed RNA polymerases I and III subunit RPAC1, DNA-directed RNA polymerase I subunit C, DNA-directed RNA polymerases I and III 40 kDa polypeptide, RNA polymerases I and III subunit AC1, polymerase (RNA) I polypeptide C, 30kDa, polymerase (RNA) I subunit C

Genomic Location:

Chr 6: 43592769-43605092

Description:

The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.

The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TMTCGCGANR_UNKNOWN ,  TTGTTT_FOXO4_01 ,  SCGGAAGY_ELK1_02

Cytogenetic Map:

6p21.1

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