QuickView for POU2F1;jsessionid=2E7320EE7A7214E343884365515C79E3 (gene)
- Gene Symbol:
- POU2F1
Homo sapiens - Full name:
- POU class 2 homeobox 1
- Synonyms:
- OCT1, OTF1, oct-1B, POU domain, class 2, transcription factor 1, NF-A1, OTF-1, Octamer-binding transcription factor-1, oct-1, octamer-binding protein 1, octamer-binding transcription factor 1
- Genomic Location:
- Chr 1: 165456767-165651966
- Description:
-
The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
FOXO1_02 , POU6F1_01 , SP1_01 , NFMUE1_Q6 , RTAAACA_FREAC2_01 , OCT1_05 , FREAC7_01 , SMTTTTGT_UNKNOWN , GCGSCMNTTT_UNKNOWN , PU1_Q6
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
1q24.2
| Transcripts Names |
|---|
| NM_002697 |
| NM_001198783 |
| NM_001198786 |
| NR_037163 |
| XM_024447727 |
| XM_011509655 |
| XM_011509654 |
| XM_011509653 |
| XM_017001508 |
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | core promoter binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | RNA polymerase II core promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | core promoter sequence-specific DNA binding | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | snRNA metabolic process | response to cytokine | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | positive regulation of cellular biosynthetic process | cellular process | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | snRNA transcription | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | response to stimulus | cellular nitrogen compound biosynthetic process | snRNA transcription by RNA polymerase II | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | ncRNA transcription | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | cytokine-mediated signaling pathway | regulation of transcription by RNA polymerase II | cellular response to cytokine stimulus | biosynthetic process | aromatic compound biosynthetic process | cell communication | regulation of cellular metabolic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | response to organic substance | cell surface receptor signaling pathway | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription, DNA-templated | signaling | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | positive regulation of transcription, DNA-templated | ncRNA metabolic process | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | signal transduction | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
nuclear transcription factor complex | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | endoplasmic reticulum | protein-containing complex | endomembrane system | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
