QuickView for PPCS (gene)

Gene Symbol:

PPCS Homo sapiens

Full name:

phosphopantothenoylcysteine synthetase

Synonyms:

phosphopantothenate--cysteine ligase, PPC synthetase

Genomic Location:

Chr 1: 42694760-42698673

Description:

Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCS (EC 6.3.2.5), one of the last enzymes in this pathway, converts phosphopantothenate to phosphopantothenoylcysteine (Daugherty et al., 2002 [PubMed 11923312]).

Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCS (EC 6.3.2.5), one of the last enzymes in this pathway, converts phosphopantothenate to phosphopantothenoylcysteine (Daugherty et al., 2002 [PubMed 11923312]).

View Less

Orthologs:

Mus musculus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_03 ,  USF_Q6 ,  TCANNTGAY_SREBP1_01 ,  MYCMAX_03 ,  CACGTG_MYC_Q2 ,  FXR_IR1_Q6 ,  ARNT_02 ,  GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 ,  SREBP1_01 ,  USF_01 ,  USF2_Q6 ,  USF_02

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-25

Cytogenetic Map:

1p34.2

search → result