QuickView for PPP1R9B (gene)

Gene Symbol:

PPP1R9B Homo sapiens

Full name:

protein phosphatase 1 regulatory subunit 9B

Synonyms:

PPP1R6, PPP1R9, SPINO, Spn, neurabin-2, neurabin-II, protein phosphatase 1, regulatory (inhibitor) subunit 9B, protein phosphatase 1, regulatory subunit 9B, spinophilin

Genomic Location:

Chr 17: 45566100-45582876

Description:

This gene encodes a scaffold protein that functions as a regulatory subunit of protein phosphatase 1a. Expression of this gene is particularly high in dendritic spines, suggesting that the encoded protein may play a role in receiving signals from the central nervous system. The encoded protein has putative tumor suppressor function and decreased ex...

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This gene encodes a scaffold protein that functions as a regulatory subunit of protein phosphatase 1a. Expression of this gene is particularly high in dendritic spines, suggesting that the encoded protein may play a role in receiving signals from the central nervous system. The encoded protein has putative tumor suppressor function and decreased expression has been observed in tumors.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  TCTGGAC_MIR198 ,  AP1_C ,  TGANTCA_AP1_C ,  USF_Q6 ,  CCCAGAG_MIR326 ,  ETS_Q4 ,  RYTTCCTG_ETS2_B ,  E2F1_Q4_01 ,  CACGTG_MYC_Q2 ,  GGGACCA_MIR133A_MIR133B ,  TGAGATT_MIR216 ,  E2F_Q6_01 ,  AREB6_04 ,  STAT1_03 ,  E2A_Q2 ,  MYCMAX_B ,  E2F1_Q4 ,  GGGAGGRR_MAZ_Q6 ,  STAT_Q6 ,  TFIII_Q6 ,  MYCMAX_02 ,  RP58_01 ,  GGCAGAC_MIR346 ,  CAGGTG_E12_Q6 ,  AP1_01 ,  ETS2_B ,  AP4_01 ,  AP1FJ_Q2 ,  EGR_Q6 ,  GAGCTGG_MIR337 ,  BACH2_01 ,  MYCMAX_01 ,  USF_C ,  GTGCCAA_MIR96 ,  AP1_Q2_01 ,  NERF_Q2 ,  CTCTGGA_MIR520A_MIR525 ,  E47_01 ,  GCM_Q2 ,  TGCCAAR_NF1_Q6 ,  HSF_Q6 ,  TGTTTGY_HNF3_Q6 ,  E2F_03 ,  NRF2_Q4 ,  AP1_Q4 ,  STAT_01 ,  E2F_Q4_01 ,  BACH1_01 ,  AAAYRNCTG_UNKNOWN ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  CP2_02 ,  PAX_Q6 ,  TTCYNRGAA_STAT5B_01 ,  AP1_Q2 ,  CTTTGT_LEF1_Q2 ,  CAGCTG_AP4_Q5 ,  GCTNWTTGK_UNKNOWN ,  AP4_Q5 ,  ETS1_B ,  PPARA_02 ,  E2F_Q3_01 ,  AP1_Q4_01 ,  GGGTGGRR_PAX4_03 ,  TGASTMAGC_NFE2_01

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Cytogenetic Map:

17q21.33

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