QuickView for PPP2R5C;jsessionid=7D79063078F252A7A5FB4215C87122CD (gene)

Gene Symbol:

PPP2R5C Homo sapiens

Full name:

protein phosphatase 2 regulatory subunit B'gamma

Synonyms:

B56G, B56gamma, PR61G, serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, B' alpha regulatory subunit, PP2A B subunit isoform B'-gamma, PP2A B subunit isoform B56-gamma, PP2A B subunit isoform PR61-gamma, PP2A B subunit isoform R5-gamma, protein phosphatase 2 regulatory subunit B', gamma, protein phosphatase 2, regulatory subunit B (B56), gamma isoform, protein phosphatase 2, regulatory subunit B', gamma isoform, renal carcinoma antigen NY-REN-29

Genomic Location:

Chr 14: 101345925-101463831

Description:

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subuni...

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The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  GTGCCAT_MIR183 ,  HNF1_01 ,  AAGCCAT_MIR135A_MIR135B ,  RYTTCCTG_ETS2_B ,  TTTTGAG_MIR373 ,  SYATTGTG_UNKNOWN ,  STAT6_02 ,  NFY_C ,  WGTTNNNNNAAA_UNKNOWN ,  ATGTACA_MIR493 ,  HNF1_C ,  CTTTGA_LEF1_Q2 ,  MAF_Q6 ,  OCT1_Q5_01 ,  TCF4_Q5 ,  TGAYRTCA_ATF3_Q6 ,  RGAANNTTC_HSF1_01 ,  GTAGGCA_MIR189 ,  NFY_Q6_01 ,  CTCAGGG_MIR125B_MIR125A ,  HSF1_01 ,  YY1_01 ,  TGCTGAY_UNKNOWN ,  NFY_01 ,  SPZ1_01 ,  GACTGTT_MIR212_MIR132 ,  ATF1_Q6 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  GATA4_Q3 ,  CP2_02 ,  CTGCAGY_UNKNOWN ,  GGCCAGT_MIR193A_MIR193B ,  TCCATTKW_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  ICSBP_Q6 ,  CAGCTG_AP4_Q5 ,  ISRE_01 ,  GCTNWTTGK_UNKNOWN ,  TTANWNANTGGM_UNKNOWN ,  TGACATY_UNKNOWN ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  PAX2_02 ,  HNF1_Q6 ,  LMO2COM_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-139 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-189 ,  Predicted Gene Targets for miR-193 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-216 ,  Predicted Gene Targets for miR-376c ,  Predicted Gene Targets for miR-493-5p

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Cytogenetic Map:

14q32.31

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