QuickView for PPP2R5D;jsessionid=1A144EAD3A22A878C5FED1FBFA03F4BB (gene)

Gene Symbol:

PPP2R5D Homo sapiens

Full name:

protein phosphatase 2 regulatory subunit B'delta

Synonyms:

B56D, B56delta, MRD35, serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, PP2A, B subunit, B' delta isoform, PP2A, B subunit, B56 delta isoform, PP2A, B subunit, PR61 delta isoform, PP2A, B subunit, R5 delta isoform, Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, delta isoform, protein phosphatase 2, regulatory subunit B (B56), delta isoform

Genomic Location:

Chr 6: 43060308-43088058

Description:

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subuni...

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The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  GATTGGY_NFY_Q6_01 ,  HNF4ALPHA_Q6 ,  MCAATNNNNNGCG_UNKNOWN ,  AGCYRWTTC_UNKNOWN ,  GGGACCA_MIR133A_MIR133B ,  CIZ_01 ,  LYF1_01 ,  ATGTACA_MIR493 ,  COUP_01 ,  MYAATNNNNNNNGGC_UNKNOWN ,  GGGAGGRR_MAZ_Q6 ,  CDP_01 ,  SP3_Q3 ,  CCAWYNNGAAR_UNKNOWN ,  ACCAAAG_MIR9 ,  GGGCGGR_SP1_Q6 ,  RORA1_01 ,  MTF1_Q4 ,  WTTGKCTG_UNKNOWN ,  ERR1_Q2 ,  TCF1P_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-493-5p

Cytogenetic Map:

6p21.1

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