QuickView for PRAF3 (gene)

Gene Symbol:

ARL6IP5 Homo sapiens

Full name:

ADP ribosylation factor like GTPase 6 interacting protein 5

Synonyms:

DERP11, GTRAP3-18, HSPC127, JWA, PRAF3, Yip6b, addicsin, hp22, jmx, PRA1 family protein 3, ADP-ribosylation factor GTPase 6 interacting protein 5, ADP-ribosylation factor-like 6 interacting protein 5, ADP-ribosylation factor-like protein 6-interacting protein 5, ADP-ribosylation-like factor 6 interacting protein 5, ARL-6-interacting protein 5, JM5, PRA1 domain family 3, aip-5, cytoskeleton-related vitamin A-responsive protein, dermal papilla derived protein 11, glutamate transporter EAAC1-interacting protein, glutamate transporter EEAC1-associated protein, prenylated Rab acceptor protein 2, protein JWa, putative MAPK activating protein PM27

Genomic Location:

Chr 3: 69216780-69237929

Description:

Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic a...

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Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  RYTTCCTG_ETS2_B ,  YTATTTTNR_MEF2_02 ,  STAT1_03 ,  CAGGTG_E12_Q6 ,  GGGCGGR_SP1_Q6 ,  CTTTAAR_UNKNOWN ,  STAT_01 ,  MSX1_01 ,  CAGCTG_AP4_Q5 ,  ELF1_Q6 ,  MEF2_Q6_01

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Cytogenetic Map:

3p14.1

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