QuickView for PRKACB (gene)

Gene Symbol:

PRKACB Homo sapiens

Full name:

protein kinase cAMP-activated catalytic subunit beta

Synonyms:

PKA C-beta, PKACB, cAMP-dependent protein kinase catalytic subunit beta, cAMP-dependent protein kinase catalytic beta subunit isoform 4ab, protein kinase A catalytic subunit beta, protein kinase, cAMP-dependent, beta catalytic subunit, protein kinase, cAMP-dependent, catalytic, beta

Genomic Location:

Chr 1: 84316333-84476769

Description:

The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spl...

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The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

STAT1_02 ,  RYTTCCTG_ETS2_B ,  PEA3_Q6 ,  TEL2_Q6 ,  HP1SITEFACTOR_Q6 ,  CAGTGTT_MIR141_MIR200A ,  WGTTNNNNNAAA_UNKNOWN ,  TATAAA_TATA_01 ,  GGTGTGT_MIR329 ,  GCACCTT_MIR18A_MIR18B ,  CAGGTA_AREB6_01 ,  GTGACGY_E4F1_Q6 ,  TST1_01 ,  HNF4_Q6 ,  GGGCGGR_SP1_Q6 ,  MGGAAGTG_GABP_B ,  HFH4_01 ,  TTGCCAA_MIR182 ,  CETS1P54_01 ,  SCGGAAGY_ELK1_02 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  TEF_Q6 ,  NRF2_01 ,  AAGCACT_MIR520F ,  E2F_Q2 ,  CCGNMNNTNACG_UNKNOWN ,  CDC5_01 ,  ELK1_02 ,  P300_01 ,  AACTTT_UNKNOWN ,  GGCAGTG_MIR3243P ,  CTAGGAA_MIR384 ,  ETF_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-18 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-193 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-324-3p ,  Predicted Gene Targets for miR-329 ,  Predicted Gene Targets for miR-34 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-384

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Cytogenetic Map:

1p31.1

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