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QuickView for PRKCB (gene)


Gene Symbol:
PRKCB Homo sapiens Homo sapiens
Full name:
protein kinase C beta
Synonyms:
PKC-beta, PKCB, PRKCB1, PRKCB2, protein kinase C beta type, PKC-B, protein kinase C, beta 1 polypeptide
Genomic Location:
Chr 16: 23754823-24139063
Description:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbo...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 16
16p12.2-p12.1





GO Molecular Function

histone threonine kinase activity | kinase binding | calcium-dependent protein kinase activity | cation binding | hormone receptor binding | protein kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | signaling receptor binding | carbohydrate derivative binding | protein serine/threonine kinase activity | protein kinase C activity | catalytic activity | chromatin binding | ATP binding | protein kinase C binding | anion binding | adenyl nucleotide binding | androgen receptor binding | calcium-dependent protein serine/threonine kinase activity | purine nucleotide binding | nuclear hormone receptor binding | calcium-dependent protein kinase C activity | ion binding | organic cyclic compound binding | transcription coactivator activity | purine ribonucleoside triphosphate binding | protein binding | zinc ion binding | transcription factor binding | histone kinase activity | transferase activity, transferring phosphorus-containing groups | nuclear receptor transcription coactivator activity | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | histone binding | transition metal ion binding | purine ribonucleotide binding | adenyl ribonucleotide binding | steroid hormone receptor binding | drug binding | kinase activity | histone kinase activity (H3-T6 specific) | transcription coregulator activity | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

positive regulation of immune response | RNA metabolic process | adaptive immune response | nucleus organization | negative regulation of cellular response to insulin stimulus | positive regulation of macromolecule biosynthetic process | histone threonine kinase activity | immune response-regulating signaling pathway | intracellular signal transduction | regulation of localization | positive regulation of DNA-binding transcription factor activity | peptidyl-amino acid modification | establishment of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | histone modification | immune response-activating cell surface receptor signaling pathway | calcium-dependent protein kinase activity | membrane organization | positive regulation of vascular endothelial growth factor receptor signaling pathway | positive regulation of cellular biosynthetic process | cellular process | localization | chromatin organization | protein transport | negative regulation of signaling | regulation of vascular endothelial growth factor receptor signaling pathway | macromolecule localization | hemostasis | endomembrane system organization | membrane disassembly | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | regulation of cell differentiation | regulation of angiogenesis | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | regulation of vasculature development | response to stimulus | peptidyl-threonine phosphorylation | positive regulation of antigen receptor-mediated signaling pathway | positive regulation of immune system process | response to stress | cellular nitrogen compound biosynthetic process | negative regulation of glucose transmembrane transport | mitotic nuclear envelope disassembly | protein serine/threonine kinase activity | programmed cell death | protein kinase C activity | cellular nitrogen compound metabolic process | lipoprotein transport | immune response-activating signal transduction | negative regulation of transport | nuclear envelope organization | positive regulation of RNA biosynthetic process | protein modification process | cellular biosynthetic process | macromolecule modification | negative regulation of transmembrane transport | B cell receptor signaling pathway | blood coagulation | regulation of nucleic acid-templated transcription | apoptotic process | nitrogen compound metabolic process | regulation of signal transduction | phosphorus metabolic process | wound healing | regulation of gene expression | platelet activation | organic substance transport | cell cycle | positive regulation of cellular metabolic process | calcium-dependent protein serine/threonine kinase activity | regulation of nitrogen compound metabolic process | negative regulation of insulin receptor signaling pathway | peptide transport | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | B cell activation | biosynthetic process | calcium-dependent protein kinase C activity | aromatic compound biosynthetic process | histone H3-T6 phosphorylation | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | nuclear envelope disassembly | cell communication | regulation of cellular metabolic process | positive regulation of signal transduction | transcription coactivator activity | regulation of RNA metabolic process | histone phosphorylation | regulation of cellular response to growth factor stimulus | coagulation | lymphocyte activation | positive regulation of molecular function | activation of immune response | protein metabolic process | regulation of hemopoiesis | histone kinase activity | response to wounding | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | mitotic cell cycle | cell surface receptor signaling pathway | metabolic process | regulation of RNA biosynthetic process | regulation of body fluid levels | nuclear receptor transcription coactivator activity | amide transport | immune response | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | cell death | regulation of glucose transmembrane transport | regulation of insulin receptor signaling pathway | gene expression | positive regulation of NF-kappaB transcription factor activity | regulation of cellular response to insulin stimulus | antigen receptor-mediated signaling pathway | establishment of protein localization | transcription, DNA-templated | cell activation | regulation of cell communication | negative regulation of signal transduction | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | covalent chromatin modification | regulation of transcription, DNA-templated | protein localization | cellular protein metabolic process | cellular macromolecule biosynthetic process | regulation of developmental process | kinase activity | organelle organization | positive regulation of B cell receptor signaling pathway | peptidyl-serine phosphorylation | cellular protein modification process | histone kinase activity (H3-T6 specific) | regulation of transport | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | regulation of B cell receptor signaling pathway | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | immune system process | cellular metabolic process | positive regulation of angiogenesis | regulation of I-kappaB kinase/NF-kappaB signaling | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane