QuickView for PRKX;jsessionid=E715B7BC3059BCC00263C2FF6BC167F2 (gene)

Gene Symbol:

PRKX Homo sapiens

Full name:

protein kinase, X-linked

Synonyms:

PKX1, cAMP-dependent protein kinase catalytic subunit PRKX, protein kinase PKX1, protein kinase X, serine/threonine-protein kinase PRKX

Genomic Location:

Chr X: 3532411-3641661

Description:

This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between t...

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This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACTGTG_MIR128A_MIR128B ,  CCAGGTT_MIR490 ,  ACTGTGA_MIR27A_MIR27B ,  GTTTGTT_MIR495

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-490 ,  Predicted Gene Targets for miR-495

Cytogenetic Map:

Xp22.33

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