QuickView for PRMT3;jsessionid=A88EEF2C77B7E0C5B0FA315E542A1B18 (gene)
- Gene Symbol:
- PRMT3
Homo sapiens - Full name:
- protein arginine methyltransferase 3
- Synonyms:
- HRMT1L3, protein arginine N-methyltransferase 3, HMT1 hnRNP methyltransferase-like 3, heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3
- Genomic Location:
- Chr 11: 20365679-20487349
- Description:
-
This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome. Alternative splicing r...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
11p15.1
| Transcripts Names |
|---|
| NM_005788 |
| NM_001145166 |
| NM_001145167 |
| XR_001747718 |
| XM_017017081 |
| XR_002957114 |
| XM_024448312 |
| XM_011519836 |
GO Molecular Function
protein methyltransferase activity | cation binding | nucleic acid binding | S-adenosylmethionine-dependent methyltransferase activity | catalytic activity | histone-arginine N-methyltransferase activity | arginine N-methyltransferase activity | protein-arginine omega-N asymmetric methyltransferase activity | histone methyltransferase activity | ion binding | protein-arginine N-methyltransferase activity | organic cyclic compound binding | protein binding | N-methyltransferase activity | transferase activity | methyltransferase activity | metal ion binding | heterocyclic compound binding
GO Biological Process
histone arginine methylation | peptidyl-amino acid modification | negative regulation of cellular process | histone modification | protein methyltransferase activity | cellular process | chromatin organization | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | S-adenosylmethionine-dependent methyltransferase activity | cellular component organization | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine | regulation of protein ubiquitination | peptidyl-arginine omega-N-methylation | negative regulation of metabolic process | protein modification process | macromolecule modification | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | histone methylation | histone-arginine N-methyltransferase activity | regulation of gene expression | arginine N-methyltransferase activity | methylation | protein-arginine omega-N asymmetric methyltransferase activity | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | histone methyltransferase activity | protein-arginine N-methyltransferase activity | peptidyl-arginine methylation | regulation of cellular metabolic process | peptidyl-arginine N-methylation | regulation of protein metabolic process | regulation of RNA metabolic process | negative regulation of protein ubiquitination | protein metabolic process | N-methyltransferase activity | metabolic process | regulation of RNA biosynthetic process | organic substance metabolic process | negative regulation of cellular protein metabolic process | negative regulation of protein metabolic process | covalent chromatin modification | regulation of transcription, DNA-templated | cellular protein metabolic process | protein methylation | methyltransferase activity | organelle organization | cellular protein modification process | chromosome organization | cellular metabolic process | macromolecule metabolic process
GO Cellular Component
cell | cytoplasm | intracellular organelle | ribosome | protein-containing complex | ribonucleoprotein complex | organelle | cytosol | intracellular
