QuickView for PROCR (gene)

Gene Symbol:

PROCR Homo sapiens

Full name:

protein C receptor

Synonyms:

CCCA, CCD41, EPCR, endothelial protein C receptor, APC receptor, CD201 antigen, activated protein C receptor, cell cycle, centrosome-associated protein, centrocyclin, protein C receptor, endothelial

Genomic Location:

Chr 20: 33223435-33228826

Description:

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infar...

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The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AP1_C ,  TGANTCA_AP1_C ,  NKX3A_01 ,  GFI1_01 ,  CACBINDINGPROTEIN_Q6 ,  GGGTGGRR_PAX4_03 ,  TGASTMAGC_NFE2_01

Cytogenetic Map:

20q11.22

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