QuickView for PSMB4 (gene)
- Gene Symbol:
- PSMB4
Homo sapiens - Full name:
- proteasome subunit beta 4
- Synonyms:
- HN3, HsN3, PROS-26, PROS26, proteasome subunit beta type-4, 26 kDa prosomal protein, hsBPROS26, macropain beta chain, multicatalytic endopeptidase complex beta chain, proteasome (prosome, macropain) subunit, beta type, 4, proteasome beta chain, proteasome chain 3, proteasome subunit HsN3, proteasome subunit, beta type, 4, testis tissue sperm-binding protein Li 79P
- Genomic Location:
- Chr 1: 149638665-149641036
- Description:
-
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and ...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
1q21.3
GO Molecular Function
lipid binding | hydrolase activity | carbohydrate derivative binding | catalytic activity | threonine-type endopeptidase activity | protein binding | lipopolysaccharide binding | endopeptidase activity | peptidase activity
GO Biological Process
protein modification by small protein removal | negative regulation of immune system process | proteolysis | regulation of immune system process | cellular process | organic substance catabolic process | negative regulation of inflammatory response | proteolysis involved in cellular protein catabolic process | interspecies interaction between organisms | regulation of immune response | catabolic process | protein deubiquitination | cellular protein catabolic process | proteasomal protein catabolic process | protein modification process | macromolecule modification | nitrogen compound metabolic process | protein catabolic process | threonine-type endopeptidase activity | negative regulation of immune response | proteasomal ubiquitin-independent protein catabolic process | viral process | proteasome-mediated ubiquitin-dependent protein catabolic process | protein metabolic process | cellular macromolecule catabolic process | metabolic process | organic substance metabolic process | protein modification by small protein conjugation or removal | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | endopeptidase activity | cellular protein metabolic process | cellular protein modification process | cellular metabolic process | peptidase activity | negative regulation of inflammatory response to antigenic stimulus | modification-dependent protein catabolic process | regulation of inflammatory response | post-translational protein modification | macromolecule metabolic process
GO Cellular Component
proteasome core complex | intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | cytoplasm | proteasome complex | intracellular organelle | protein-containing complex | nucleoplasm | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | proteasome core complex, beta-subunit complex | membrane-enclosed lumen | cytosol | intracellular
