QuickView for PSMD10 (gene)

Gene Symbol:

PSMD10 Homo sapiens

Full name:

proteasome 26S subunit, non-ATPase 10

Synonyms:

dJ889N15.2, p28, p28(GANK), 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit p28, ankyrin repeat protein, gankyrin, hepatocellular carcinoma-associated protein p28-II, proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

Genomic Location:

Chr X: 107214093-107221504

Description:

This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesi...

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This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RGAANNTTC_HSF1_01 ,  CCTGTGA_MIR513 ,  AAAGACA_MIR511

Cytogenetic Map:

Xq22.3

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