QuickView for PTH (gene)

Gene Symbol:

PTH Homo sapiens

Full name:

parathyroid hormone

Synonyms:

PTH1, parathyroid hormone, parathormone, parathyrin, parathyroid hormone 1, prepro-PTH, preproparathyroid hormone

Genomic Location:

Chr 11: 13470177-13474143

Description:

This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, ca...

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This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGAYRTCA_ATF3_Q6 ,  TATAAA_TATA_01 ,  TGACATY_UNKNOWN

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-503

Cytogenetic Map:

11p15.3

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