QuickView for PTP4A3;jsessionid=49E79E59D8C7011D82F2F014999F5ACE (gene)

Gene Symbol:

PTP4A3 Homo sapiens

Full name:

protein tyrosine phosphatase type IVA, member 3

Synonyms:

PRL-3, PRL-R, PRL3, protein tyrosine phosphatase type IVA 3, phosphatase of regenerating liver 3, potentially prenylated protein tyrosine phosphatase, protein-tyrosine phosphatase 4a3, protein-tyrosine phosphatase of regenerating liver 3

Genomic Location:

Chr 8: 142501189-142510802

Description:

This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma me...

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This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris ,  Pan troglodytes ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RTAAACA_FREAC2_01 ,  GATA1_01 ,  FOXO4_01 ,  CAGGTG_E12_Q6 ,  CAGCTG_AP4_Q5

Cytogenetic Map:

8q24.3

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