QuickView for Polg2 (gene)

Gene Symbol:

POLG2 Homo sapiens

Full name:

DNA polymerase gamma 2, accessory subunit

Synonyms:

HP55, MTPOLB, PEOA4, POLB, POLG-BETA, POLGB, DNA polymerase subunit gamma-2, mitochondrial, DNA polymerase gamma accessory 55 kDa subunit, mitochondrial DNA polymerase subunit gamma-2, mitochondrial DNA polymerase, accessory subunit, p55, polymerase (DNA directed), gamma 2, accessory subunit, polymerase (DNA) gamma 2, accessory subunit

Genomic Location:

Chr 17: 59904364-59923631

Description:

This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmopleg...

View Full Description

This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  AML_Q6 ,  E4BP4_01 ,  FAC1_01 ,  YAATNRNNNYNATT_UNKNOWN ,  CAGGTG_E12_Q6 ,  OCT1_06 ,  RACCACAR_AML_Q6 ,  AFP1_Q6 ,  GGGTGGRR_PAX4_03

Cytogenetic Map:

17q23.3

search → result