QuickView for Ppp1r15a (gene)

Gene Symbol:

PPP1R15A Homo sapiens

Full name:

protein phosphatase 1 regulatory subunit 15A

Synonyms:

GADD34, protein phosphatase 1 regulatory subunit 15A, growth arrest and DNA damage-inducible protein GADD34, growth arrest and DNA-damage-inducible 34, myeloid differentiation primary response protein MyD116 homolog, protein phosphatase 1, regulatory (inhibitor) subunit 15A

Genomic Location:

Chr 19: 54067461-54071131

Description:

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiatio...

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This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AP1_C ,  TGANTCA_AP1_C ,  CREBP1CJUN_01 ,  CREB_Q4_01 ,  ATF4_Q2 ,  CREB_Q4 ,  TGAYRTCA_ATF3_Q6 ,  ATF_B ,  CREBP1_Q2 ,  TATAAA_TATA_01 ,  AP1_Q6_01 ,  GTGACGY_E4F1_Q6 ,  ATF_01 ,  CREB_02 ,  ATF3_Q6 ,  TGCTGAY_UNKNOWN ,  E4F1_Q6 ,  BACH1_01 ,  CREB_Q2 ,  TGACGTCA_ATF3_Q6 ,  AP1_Q4_01 ,  CREB_Q2_01 ,  CREB_01

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Cytogenetic Map:

19q13.33

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