QuickView for Praja1 (gene)
- Gene Symbol:
- PJA1
Homo sapiens - Full name:
- praja ring finger ubiquitin ligase 1
- Synonyms:
- PRAJA1, RNF70, E3 ubiquitin-protein ligase Praja-1, RING finger protein 70, RING-type E3 ubiquitin transferase Praja-1, praja 1, praja ring finger 1, E3 ubiquitin protein ligase
- Genomic Location:
- Chr X: 68297422-68302065
- Description:
-
This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked cognitive disability disorders have ...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
Xq13.1
GO Molecular Function
cation binding | catalytic activity | ubiquitin-like protein transferase activity | ubiquitin protein ligase activity | ion binding | protein binding | ubiquitin-protein transferase activity | transferase activity | ubiquitin-like protein ligase activity | metal ion binding
GO Biological Process
cellular process | organic substance catabolic process | catabolic process | protein modification process | macromolecule modification | nitrogen compound metabolic process | protein catabolic process | protein modification by small protein conjugation | ubiquitin protein ligase activity | protein metabolic process | protein ubiquitination | metabolic process | ubiquitin-protein transferase activity | organic substance metabolic process | protein modification by small protein conjugation or removal | organonitrogen compound catabolic process | cellular protein metabolic process | cellular protein modification process | cellular metabolic process | macromolecule metabolic process
