QuickView for Prop1 (gene)

Gene Symbol:

PROP1 Homo sapiens

Full name:

PROP paired-like homeobox 1

Synonyms:

CPHD2, PROP-1, homeobox protein prophet of Pit-1, pituitary-specific homeodomain factor, prophet of Pit1, paired-like homeodomain transcription factor

Genomic Location:

Chr 5: 177351842-177355849

Description:

This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficie...

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This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RYTTCCTG_ETS2_B ,  ARP1_01 ,  CAGGTG_E12_Q6 ,  S8_01 ,  NF1_Q6_01 ,  TAATTA_CHX10_01 ,  WGGAATGY_TEF1_Q6 ,  IK1_01

Cytogenetic Map:

5q35.3

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