QuickView for Ptgfr (gene)

Gene Symbol:

PTGFR Homo sapiens

Full name:

prostaglandin F receptor

Synonyms:

FP, prostaglandin F2-alpha receptor, FP prostanoid receptor, PGF receptor, PGF2 alpha receptor, prostaglandin receptor (2-alpha), prostanoid FP receptor

Genomic Location:

Chr 1: 78729316-78778974

Description:

The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the intera...

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The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TCANNTGAY_SREBP1_01 ,  TGGNNNNNNKCCAR_UNKNOWN ,  AP3_Q6 ,  EVI1_04 ,  AACTGGA_MIR145 ,  PAX4_02 ,  CAGGTG_E12_Q6 ,  EVI1_02 ,  EVI1_05 ,  YTAAYNGCT_UNKNOWN

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-145

Cytogenetic Map:

1p31.1

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