QuickView for QC (gene)

Gene Symbol:

QPCT Homo sapiens

Full name:

glutaminyl-peptide cyclotransferase

Synonyms:

GCT, QC, sQC, glutaminyl-peptide cyclotransferase, EC, glutaminyl cyclase, glutaminyl-tRNA cyclotransferase, glutamyl cyclase

Genomic Location:

Chr 2: 37425257-37453969

Description:

This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.

This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RYTTCCTG_ETS2_B ,  WTGAAAT_UNKNOWN ,  TGAYRTCA_ATF3_Q6 ,  STAT_Q6 ,  TGACATY_UNKNOWN ,  GGGTGGRR_PAX4_03

Cytogenetic Map:

2p22.2

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