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QuickView for RAB1B;jsessionid=4226E4099195EB30415B68E4D2F063F5 (gene)


Gene Symbol:
RAB1B Homo sapiens Homo sapiens
Full name:
RAB1B, member RAS oncogene family
Synonyms:
ras-related protein Rab-1B, small GTP-binding protein
Genomic Location:
Chr 11: 65792632-65801539
Description:
Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 11
11q13.2


Transcripts Names
NM_030981
XM_001134089
XM_017018378
Protein Names
Q9H0U4
A8K7S1



GO Molecular Function

guanyl ribonucleotide binding | ribonucleoside binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | GTP binding | hydrolase activity, acting on acid anhydrides | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding

GO Biological Process

intracellular signal transduction | endothelial cell development | regulation of vacuole organization | establishment of localization | regulation of autophagy | cell differentiation | endothelial cell differentiation | regulation of organelle organization | membrane organization | intracellular transport | cellular process | establishment of organelle localization | localization | protein transport | macromolecule localization | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | tissue development | regulation of autophagosome assembly | vesicle targeting, to, from or within Golgi | interspecies interaction between organisms | regulation of cellular process | regulation of metabolic process | catabolic process | organelle localization | small GTPase mediated signal transduction | epithelium development | cellular component organization | viral life cycle | response to stimulus | positive regulation of protein metabolic process | COPII-coated vesicle budding | intracellular protein transport | epithelial cell development | cellular localization | regulation of macroautophagy | cellular component assembly | protein modification process | macromolecule modification | vesicle targeting | nitrogen compound metabolic process | endothelium development | retrograde vesicle-mediated transport, Golgi to ER | vesicle coating | organic substance transport | positive regulation of cellular metabolic process | establishment of endothelial barrier | regulation of nitrogen compound metabolic process | peptide transport | vesicle-mediated transport | Golgi vesicle budding | establishment of vesicle localization | autophagy | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | establishment of endothelial intestinal barrier | Golgi vesicle transport | viral process | protein-containing complex assembly | protein metabolic process | anatomical structure development | metabolic process | Rab protein signal transduction | cellular protein localization | virion assembly | amide transport | organic substance metabolic process | establishment of protein localization | vesicle organization | positive regulation of glycoprotein metabolic process | vesicle budding from membrane | ER to Golgi vesicle-mediated transport | signaling | cell development | protein localization | cellular protein metabolic process | cellular macromolecule localization | developmental process | organelle organization | COPII vesicle coating | cellular protein modification process | Ras protein signal transduction | epithelial cell differentiation | positive regulation of metabolic process | vesicle localization | cellular metabolic process | regulation of organelle assembly | regulation of cellular component organization | signal transduction | post-translational protein modification | macromolecule metabolic process

GO Cellular Component

endoplasmic reticulum-Golgi intermediate compartment | intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | phagophore assembly site membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | Golgi apparatus | phagophore assembly site | nuclear outer membrane-endoplasmic reticulum membrane network | endoplasmic reticulum-Golgi intermediate compartment membrane | endomembrane system | endoplasmic reticulum membrane | vesicle | transport vesicle | extracellular exosome | Golgi membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cytosol | intracellular vesicle | intracellular | membrane