QuickView for RAB7A (gene)

Gene Symbol:

RAB7A Homo sapiens

Full name:

RAB7A, member RAS oncogene family

Synonyms:

PRO2706, RAB7, ras-related protein Rab-7a, RAB7, member RAS oncogene family, Ras-associated protein RAB7

Genomic Location:

Chr 3: 129927669-130016331

Description:

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded ...

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RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Canis lupus familiaris ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CGTSACG_PAX3_B ,  TGGAAA_NFAT_Q4_01 ,  GABP_B ,  GCANCTGNY_MYOD_Q6 ,  AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D ,  ATF4_Q2 ,  CTTTGA_LEF1_Q2 ,  CREB_Q4 ,  GGGAGGRR_MAZ_Q6 ,  GTGACGY_E4F1_Q6 ,  CATRRAGC_UNKNOWN ,  ATGTTAA_MIR302C ,  MGGAAGTG_GABP_B ,  AP2_Q3 ,  ATATGCA_MIR448 ,  SCGGAAGY_ELK1_02 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  CREB_Q2 ,  TCCATTKW_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  PAX3_B ,  TCATCTC_MIR143

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Cytogenetic Map:

3q21.3

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