QuickView for RACGAP1 (gene)

Gene Symbol:

RACGAP1 Homo sapiens

Full name:

Rac GTPase activating protein 1

Synonyms:

CYK4, HsCYK-4, ID-GAP, MgcRacGAP, rac GTPase-activating protein 1, male germ cell RacGap, protein CYK4 homolog

Genomic Location:

Chr 12: 48669212-48705488

Description:

This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively sp...

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This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  GATTGGY_NFY_Q6_01 ,  NFY_C ,  GCCATNTTG_YY1_Q6 ,  NFY_Q6_01 ,  NFY_01 ,  NFY_Q6

Cytogenetic Map:

12q13.12

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