QuickView for RAMP2 (gene)

Gene Symbol:

RAMP2 Homo sapiens

Full name:

receptor activity modifying protein 2

Synonyms:

receptor activity-modifying protein 2, CRLR activity-modifying protein 2, calcitonin receptor-like receptor activity modifying protein 2, receptor (G protein-coupled) activity modifying protein 2, receptor (calcitonin) activity modifying protein 2

Genomic Location:

Chr 17: 38166738-38168585

Description:

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to ...

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The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGIF_01 ,  USF_Q6 ,  RYTTCCTG_ETS2_B ,  AML_Q6 ,  CACGTG_MYC_Q2 ,  GGGAGGRR_MAZ_Q6 ,  GGGYGTGNY_UNKNOWN ,  AP4_Q6 ,  PXR_Q2 ,  MYCMAX_01 ,  GGGCGGR_SP1_Q6 ,  RNGTGGGC_UNKNOWN ,  NMYC_01 ,  USF_Q6_01 ,  IK3_01 ,  TGACAGNY_MEIS1_01 ,  CAGCTG_AP4_Q5 ,  AACTTT_UNKNOWN ,  HIF1_Q3 ,  GGARNTKYCCA_UNKNOWN ,  COREBINDINGFACTOR_Q6

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Cytogenetic Map:

17q21.2

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