QuickView for RARG (gene)

Gene Symbol:

RARG Homo sapiens

Full name:

retinoic acid receptor gamma

Synonyms:

NR1B3, RARC, retinoic acid receptor gamma, RAR-gamma, nuclear receptor subfamily 1 group B member 3, retinoic acid nuclear receptor gamma variant 1, retinoic acid nuclear receptor gamma variant 2

Genomic Location:

Chr 12: 51890620-51912303

Description:

This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target gen...

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This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  RTAAACA_FREAC2_01 ,  CACTGCC_MIR34A_MIR34C_MIR449 ,  GATA1_01 ,  USF_Q6 ,  CCCAGAG_MIR326 ,  VDR_Q3 ,  TGANNYRGCA_TCF11MAFG_01 ,  CACGTG_MYC_Q2 ,  EVI1_04 ,  LYF1_01 ,  AP2GAMMA_01 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  CAGCACT_MIR5123P ,  TAGCTTT_MIR9 ,  SREBP1_Q6 ,  MYB_Q5_01 ,  AP2ALPHA_01 ,  GGGAGGRR_MAZ_Q6 ,  TATAAA_TATA_01 ,  TFIII_Q6 ,  GCTGAGT_MIR5125P ,  DBP_Q6 ,  CACCCBINDINGFACTOR_Q6 ,  GGGYGTGNY_UNKNOWN ,  RP58_01 ,  CAGGTG_E12_Q6 ,  PXR_Q2 ,  HNF3B_01 ,  GGGCGGR_SP1_Q6 ,  IRF_Q6 ,  USF_01 ,  NRF2_Q4 ,  AHRARNT_01 ,  RNGTGGGC_UNKNOWN ,  MYB_Q6 ,  GTGCCTT_MIR506 ,  TTGCCAA_MIR182 ,  WGGAATGY_TEF1_Q6 ,  GTCNYYATGR_UNKNOWN ,  ARGGGTTAA_UNKNOWN ,  CCAGGGG_MIR331 ,  CTGAGCC_MIR24 ,  ZIC2_01 ,  T3R_Q6 ,  RYAAAKNNNNNNTTGW_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  LXR_Q3 ,  USF2_Q6 ,  P300_01 ,  FREAC4_01 ,  ACACTAC_MIR1423P ,  GGGTGGRR_PAX4_03 ,  LMO2COM_01 ,  MYB_Q3

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-142-3p ,  Predicted Gene Targets for miR-24 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-326 ,  Predicted Gene Targets for miR-331 ,  Predicted Gene Targets for miR-34 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-182

miRNA binding sites
(Source: miRecords):

hsa-miR-124 Targeted Genes

Cytogenetic Map:

12q13.13

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