QuickView for RC3H2;jsessionid=0D9678E35C2B6DA45CC5B3FC6E3569B0 (gene)
- Gene Symbol:
- RC3H2
Homo sapiens - Full name:
- ring finger and CCCH-type domains 2
- Synonyms:
- MNAB, RNF164, roquin-2, RING finger protein 164, RING-type E3 ubiquitin transferase Roquin-2, membrane associated DNA binding protein, membrane-associated nucleic acid-binding protein, ring finger and CCCH-type zinc finger domain-containing protein 2, ring finger and CCCH-type zinc finger domains 2
- Genomic Location:
- Chr 9: 124651553-124707383
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
9q33.2
GO Molecular Function
RNA stem-loop binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cation binding | nucleic acid binding | mRNA binding | catalytic activity | ubiquitin-like protein transferase activity | DNA binding | ion binding | organic cyclic compound binding | DNA-binding transcription factor activity | ubiquitin-protein transferase activity | transferase activity | metal ion binding | heterocyclic compound binding | RNA binding | double-stranded RNA binding
GO Biological Process
positive regulation of immune response | negative regulation of lymphocyte differentiation | leukocyte homeostasis | negative regulation of leukocyte activation | limb development | negative regulation of immune system process | CD4-positive, alpha-beta T cell differentiation | CD4-positive, alpha-beta T cell activation | immune response-regulating signaling pathway | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | regulation of T-helper 17 type immune response | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of leukocyte cell-cell adhesion | cell differentiation | immune response-activating cell surface receptor signaling pathway | regulation of T cell differentiation | respiratory tube development | T cell receptor signaling pathway | multicellular organism growth | cellular process | lymphocyte differentiation | developmental growth | immune system development | negative regulation of alpha-beta T cell differentiation | negative regulation of T-helper 17 cell differentiation | regulation of cell differentiation | negative regulation of CD4-positive, alpha-beta T cell activation | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | T cell differentiation involved in immune response | T cell activation | response to stimulus | positive regulation of NIK/NF-kappaB signaling | respiratory system development | alpha-beta T cell activation involved in immune response | positive regulation of immune system process | negative regulation of cell adhesion | regulation of CD4-positive, alpha-beta T cell activation | mononuclear cell proliferation | negative regulation of lymphocyte activation | leukocyte activation involved in immune response | posttranscriptional regulation of gene expression | immune response-activating signal transduction | hemopoiesis | negative regulation of hemopoiesis | protein modification process | regulation of cell adhesion | macromolecule modification | regulation of lymphocyte differentiation | negative regulation of adaptive immune response | regulation of nucleic acid-templated transcription | T-helper cell differentiation | leukocyte differentiation | lung alveolus development | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of T-helper cell differentiation | multicellular organism development | spleen development | regulation of CD4-positive, alpha-beta T cell differentiation | regulation of miRNA metabolic process | regulation of T cell activation | regulation of gene expression | negative regulation of T-helper 17 type immune response | regulation of lymphocyte activation | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | negative regulation of T cell activation | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | alpha-beta T cell differentiation | regulation of T-helper 17 cell differentiation | B cell homeostasis | homeostasis of number of cells | cell proliferation | leukocyte proliferation | negative regulation of immune response | T cell activation involved in immune response | post-embryonic development | negative regulation of cell-cell adhesion | cell communication | regulation of cellular metabolic process | regulation of alpha-beta T cell differentiation | lymphocyte homeostasis | negative regulation of cell activation | cell activation involved in immune response | regulation of NIK/NF-kappaB signaling | positive regulation of signal transduction | homeostatic process | negative regulation of CD4-positive, alpha-beta T cell differentiation | regulation of RNA metabolic process | negative regulation of T cell differentiation | lymphocyte activation | protein polyubiquitination | lymph node development | T cell differentiation | activation of immune response | protein metabolic process | DNA-binding transcription factor activity | protein ubiquitination | regulation of hemopoiesis | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | ubiquitin-protein transferase activity | regulation of adaptive immune response | regulation of RNA biosynthetic process | immune response | organic substance metabolic process | animal organ development | T cell proliferation | regulation of cell activation | alpha-beta T cell activation | protein modification by small protein conjugation or removal | antigen receptor-mediated signaling pathway | T cell homeostasis | cell activation | lung development | regulation of T-helper cell differentiation | lymphocyte proliferation | regulation of cell communication | signaling | regulation of transcription, DNA-templated | cellular protein metabolic process | T follicular helper cell differentiation | regulation of developmental process | developmental process | cellular protein modification process | negative regulation of alpha-beta T cell activation | tube development | regulation of cell-cell adhesion | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | negative regulation of cell differentiation | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | ribonucleoprotein granule | cytoplasm | intracellular organelle | P-body | protein-containing complex | ribonucleoprotein complex | membrane-bounded organelle | organelle | cytoplasmic ribonucleoprotein granule | cell surface | intracellular | membrane
