QuickView for RCN1 (gene)

Gene Symbol:

RCN1 Homo sapiens

Full name:

reticulocalbin 1

Synonyms:

HEL-S-84, PIG20, RCAL, RCN, reticulocalbin-1, epididymis secretory protein Li 84, proliferation-inducing gene 20, reticulocalbin 1, EF-hand calcium binding domain

Genomic Location:

Chr 11: 32069267-32083653

Description:

Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function bes...

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Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PR_Q2 ,  PR_01 ,  TACTTGA_MIR26A_MIR26B ,  CTTTGA_LEF1_Q2 ,  GR_Q6_01 ,  AAGCAAT_MIR137 ,  YAATNRNNNYNATT_UNKNOWN ,  SOX9_B1 ,  LEF1_Q2 ,  TAATGTG_MIR323 ,  GR_Q6 ,  AR_03 ,  SOX5_01 ,  AATGTGA_MIR23A_MIR23B ,  GR_01 ,  AAAGGAT_MIR501 ,  SRY_02

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-26 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-137

Cytogenetic Map:

11p13

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