QuickView for RCan2 (gene)
- Gene Symbol:
- RCAN2
Homo sapiens - Full name:
- regulator of calcineurin 2
- Synonyms:
- CSP2, DSCR1L1, MCIP2, RCN2, ZAKI-4, ZAKI4, calcipressin-2, Down syndrome candidate region 1-like 1, Down syndrome critical region gene 1-like 1, myocyte-enriched calcineurin-interacting protein 2, thyroid hormone-responsive (skin fibroblasts), thyroid hormone-responsive protein ZAKI-4
- Genomic Location:
- Chr 6: 46296428-46401490
- Description:
-
This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyr...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
6p12.3
GO Molecular Function
nucleic acid binding | molecular function regulator | calcium-dependent protein serine/threonine phosphatase regulator activity | organic cyclic compound binding | protein phosphatase regulator activity | enzyme regulator activity | heterocyclic compound binding | phosphatase regulator activity
GO Biological Process
regulation of dephosphorylation | intracellular signal transduction | regulation of phosphatase activity | cellular process | regulation of calcium-mediated signaling | regulation of cellular process | regulation of metabolic process | response to stimulus | molecular function regulator | regulation of signal transduction | regulation of catalytic activity | regulation of nitrogen compound metabolic process | calcium-dependent protein serine/threonine phosphatase regulator activity | second-messenger-mediated signaling | regulation of cellular protein metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | calcium-mediated signaling | regulation of protein dephosphorylation | regulation of intracellular signal transduction | protein phosphatase regulator activity | regulation of calcineurin-NFAT signaling cascade | regulation of phosphate metabolic process | regulation of cell communication | signaling | enzyme regulator activity | regulation of phosphoprotein phosphatase activity | phosphatase regulator activity | signal transduction | regulation of signaling | regulation of phosphorus metabolic process
