QuickView for RELT (gene)

Gene Symbol:

RELT Homo sapiens

Full name:

RELT, TNF receptor

Synonyms:

TNFRSF19L, TRLT, tumor necrosis factor receptor superfamily member 19L, RELT tumor necrosis factor receptor, receptor expressed in lymphoid tissues

Genomic Location:

Chr 11: 72765053-72786167

Description:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, w...

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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGANTCA_AP1_C ,  E2F1_Q4_01 ,  PEA3_Q6 ,  TAGCTTT_MIR9 ,  SOX9_B1 ,  E2F1_Q6_01 ,  SOX5_01 ,  E2F_Q4_01 ,  TTGTTT_FOXO4_01 ,  CTGCAGY_UNKNOWN ,  T3R_Q6 ,  SRY_02 ,  ERR1_Q2 ,  E2F_Q3_01 ,  SF1_Q6 ,  OLF1_01

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Cytogenetic Map:

11q13.4

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