QuickView for RGS3 (gene)

Gene Symbol:

RGS3 Homo sapiens

Full name:

regulator of G protein signaling 3

Synonyms:

C2PA, RGP3, regulator of G-protein signaling 3, regulator of G-protein signalling 3

Genomic Location:

Chr 9: 115246832-115399839

Description:

This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plas...

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This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  PR_Q2 ,  GATTGGY_NFY_Q6_01 ,  PAX4_04 ,  OCT1_05 ,  PR_02 ,  TGANTCA_AP1_C ,  ETS_Q4 ,  RYTTCCTG_ETS2_B ,  RSRFC4_01 ,  PR_01 ,  STAT6_02 ,  GCANCTGNY_MYOD_Q6 ,  TEL2_Q6 ,  RSRFC4_Q2 ,  AACTGGA_MIR145 ,  HP1SITEFACTOR_Q6 ,  WGTTNNNNNAAA_UNKNOWN ,  AMEF2_Q6 ,  CTTTGA_LEF1_Q2 ,  NKX22_01 ,  TGACCTY_ERR1_Q2 ,  GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 ,  GGGAGGRR_MAZ_Q6 ,  MEF2_02 ,  GGGNRMNNYCAT_UNKNOWN ,  TATAAA_TATA_01 ,  OCT1_Q6 ,  STAT3_02 ,  CEBPB_01 ,  SOX9_B1 ,  LEF1_Q6 ,  GGGYGTGNY_UNKNOWN ,  YYCATTCAWW_UNKNOWN ,  CEBP_01 ,  CAGGTG_E12_Q6 ,  ETS2_B ,  GR_Q6 ,  GGCNKCCATNK_UNKNOWN ,  NFY_01 ,  GATA6_01 ,  CCCNNGGGAR_OLF1_01 ,  NERF_Q2 ,  MGGAAGTG_GABP_B ,  TGTTTGY_HNF3_Q6 ,  CAGCAGG_MIR370 ,  TTGTTT_FOXO4_01 ,  GR_01 ,  WGGAATGY_TEF1_Q6 ,  RTTTNNNYTGGM_UNKNOWN ,  TEF_Q6 ,  SMAD4_Q6 ,  PAX_Q6 ,  TTCYNRGAA_STAT5B_01 ,  TAL1BETAITF2_01 ,  CTTTGT_LEF1_Q2 ,  AACTTT_UNKNOWN ,  YNGTTNNNATT_UNKNOWN ,  ETS1_B ,  NFKB_Q6 ,  SRF_C ,  CCACACA_MIR147 ,  CP2_01 ,  OLF1_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-126 ,  Predicted Gene Targets for miR-25

Cytogenetic Map:

9q32

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