QuickView for RIP2 (gene)
- Gene Symbol:
- ARHGEF28
Homo sapiens - Full name:
- Rho guanine nucleotide exchange factor 28
- Synonyms:
- RGNEF, RIP2, p190RHOGEF, rho guanine nucleotide exchange factor 28, 190 kDa guanine nucleotide exchange factor, Rho guanine nucleotide exchange factor (GEF) 28, Rho interacting protein 2, p190-RhoGEF, rho-guanine nucleotide exchange factor
- Genomic Location:
- Chr 5: 72957739-73243284
- Description:
-
This gene encodes a member of the Rho guanine nucleotide exchange factor family. The encoded protein interacts with low molecular weight neurofilament mRNA and may be involved in the formation of amyotrophic lateral sclerosis neurofilament aggregates. Alternate splicing results in multiple transcript variants.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
5q13.2
GO Molecular Function
Rho guanyl-nucleotide exchange factor activity | guanyl-nucleotide exchange factor activity | GTPase binding | Rho GTPase binding | cation binding | enzyme binding | nucleic acid binding | Ras GTPase binding | molecular function regulator | ion binding | organic cyclic compound binding | protein binding | Ras guanyl-nucleotide exchange factor activity | small GTPase binding | metal ion binding | heterocyclic compound binding | RNA binding
GO Biological Process
Rho guanyl-nucleotide exchange factor activity | guanyl-nucleotide exchange factor activity | intracellular signal transduction | cell differentiation | cellular process | regulation of cellular process | ephrin receptor signaling pathway | response to stimulus | molecular function regulator | regulation of signal transduction | regulation of small GTPase mediated signal transduction | enzyme linked receptor protein signaling pathway | regulation of Rho protein signal transduction | cell communication | regulation of intracellular signal transduction | cell surface receptor signaling pathway | Ras guanyl-nucleotide exchange factor activity | regulation of cell communication | signaling | regulation of Ras protein signal transduction | developmental process | transmembrane receptor protein tyrosine kinase signaling pathway | signal transduction | regulation of signaling
GO Cellular Component
cell | cytoplasm | plasma membrane | cell periphery | cytosol | intracellular | membrane
