QuickView for RIPK2 (gene)

Gene Symbol:

RIPK2 Homo sapiens

Full name:

receptor interacting serine/threonine kinase 2

Synonyms:

CARD3, CARDIAK, CCK, GIG30, RICK, RIP2, receptor-interacting serine/threonine-protein kinase 2, CARD-carrying kinase, CARD-containing IL-1 beta ICE-kinase, CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase, RIP-2, growth-inhibiting gene 30, receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase, receptor-interacting protein 2, tyrosine-protein kinase RIPK2

Genomic Location:

Chr 8: 90839110-90872433

Description:

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of a...

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This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ICSBP_Q6 ,  ISRE_01

Cytogenetic Map:

8q21.3

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