QuickView for RIPOR2;jsessionid=2E5D32B07A44D2F096F18DC95DF31AAC (gene)

Gene Symbol:

RIPOR2 Homo sapiens

Full name:

RHO family interacting cell polarization regulator 2

Synonyms:

C6orf32, DFNB104, DIFF40, DIFF48, FAM65B, MYONAP, PL48, rho family-interacting cell polarization regulator 2, protein FAM65B, family with sequence similarity 65 member B, myogenesis-related and NCAM-associated protein homolog

Genomic Location:

Chr 6: 24947566-24985562

Description:

This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human ...

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This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  ARP1_01 ,  CTTTAAR_UNKNOWN ,  SMAD_Q6

Cytogenetic Map:

6p22.3

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