QuickView for RLN2 (gene)

Gene Symbol:

RLN2 Homo sapiens

Full name:

relaxin 2

Synonyms:

H2, H2-RLX, RLXH2, bA12D24.1.1, bA12D24.1.2, prorelaxin H2, H2-preprorelaxin, relaxin H2, relaxin, ovarian, of pregnancy

Genomic Location:

Chr 9: 5289868-5294580

Description:

This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mat...

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This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects.

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External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CCAWYNNGAAR_UNKNOWN ,  GGGTGGRR_PAX4_03

Cytogenetic Map:

9p24.1

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