QuickView for RMI2 (gene)
- Gene Symbol:
- RMI2
Homo sapiens - Full name:
- RecQ mediated genome instability 2
- Synonyms:
- BLAP18, C16orf75, recQ-mediated genome instability protein 2, BLM-associated protein of 18 kDa, RMI2, RecQ mediated genome instability 2, homolog
- Genomic Location:
- Chr 16: 11346812-11353118
- Description:
-
RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Danio rerio , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
GATTGGY_NFY_Q6_01 , MCAATNNNNNGCG_UNKNOWN , E2F4DP1_01 , E2F_Q6_01 , E2F_01 , E2F1_Q4 , E2F_Q6 , E2F_Q4 , E2F1DP2_01 , E2F1_Q3_01
- Cytogenetic Map:
-
16p13.13
GO Molecular Function
nucleic acid binding | DNA binding | organic cyclic compound binding | heterocyclic compound binding
GO Biological Process
regulation of cell cycle process | negative regulation of cellular process | regulation of organelle organization | negative regulation of DNA metabolic process | regulation of DNA repair | regulation of chromosome segregation | cellular process | regulation of cell cycle | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | negative regulation of DNA repair | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | regulation of DNA recombination | response to stress | regulation of double-strand break repair | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | DNA repair | regulation of cellular response to stress | nitrogen compound metabolic process | cellular response to DNA damage stimulus | cellular response to stress | regulation of nitrogen compound metabolic process | negative regulation of double-strand break repair | biosynthetic process | regulation of cellular metabolic process | regulation of double-strand break repair via homologous recombination | DNA metabolic process | regulation of sister chromatid segregation | metabolic process | regulation of response to DNA damage stimulus | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of chromosome organization | negative regulation of DNA recombination | cellular macromolecule biosynthetic process | negative regulation of double-strand break repair via homologous recombination | heterocycle metabolic process | cellular metabolic process | DNA replication | regulation of cellular component organization | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | nucleoplasm | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
