Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for RND3 (gene)


Gene Symbol:
RND3 Homo sapiens Homo sapiens
Full name:
Rho family GTPase 3
Synonyms:
ARHE, Rho8, RhoE, memB, rho-related GTP-binding protein RhoE, protein MemB, ras homolog gene family, member E, rho-related GTP-binding protein Rho8, small GTP binding protein Rho8
Genomic Location:
Chr 2: 151032955-151052426
Description:
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Danio rerio Canis lupus familiaris Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 2
2q23.3


Transcripts Names
NM_005168
NM_001254738
Protein Names
P52199
P61587
B2R838
D3DP95



GO Molecular Function

kinase binding | guanyl ribonucleotide binding | ribonucleoside binding | protein kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | anion binding | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | GTPase activity | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | GTP binding | hydrolase activity, acting on acid anhydrides | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | guanyl nucleotide binding | small molecule binding

GO Biological Process

actin filament-based process | regulation of cell morphogenesis | intracellular signal transduction | regulation of localization | actin filament bundle organization | actin cytoskeleton organization | regulation of cell shape | regulation of organelle organization | cellular process | regulation of cell motility | regulation of cellular process | small GTPase mediated signal transduction | cellular component organization | response to stimulus | supramolecular fiber organization | cellular component assembly | establishment or maintenance of actin cytoskeleton polarity | regulation of actin cytoskeleton organization | actin filament organization | regulation of cell migration | regulation of cellular component movement | actin filament bundle assembly | establishment or maintenance of cell polarity | cell communication | regulation of locomotion | Rho protein signal transduction | cell adhesion | cytoskeleton organization | signaling | regulation of developmental process | organelle organization | Ras protein signal transduction | establishment or maintenance of cytoskeleton polarity | regulation of actin filament-based process | regulation of cellular component organization | regulation of cytoskeleton organization | signal transduction

GO Cellular Component

intracellular membrane-bounded organelle | adherens junction | organelle membrane | focal adhesion | cell | cytoplasm | cell-substrate junction | intracellular organelle | Golgi apparatus | endomembrane system | plasma membrane | cytoplasmic region | Golgi membrane | cell cortex | membrane-bounded organelle | organelle | cell division site | cell periphery | cell-substrate adherens junction | intracellular | cell junction | membrane