QuickView for RNF126 (gene)
- Gene Symbol:
- RNF126
Homo sapiens - Full name:
- ring finger protein 126
- Synonyms:
- E3 ubiquitin-protein ligase RNF126
- Genomic Location:
- Chr 19: 598526-614227
- Description:
-
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
19p13.3
GO Molecular Function
cation binding | signaling receptor binding | catalytic activity | ubiquitin-like protein transferase activity | ubiquitin protein ligase activity | ion binding | protein binding | ubiquitin-protein transferase activity | transferase activity | ubiquitin-like protein ligase activity | epidermal growth factor receptor binding | growth factor receptor binding | metal ion binding
GO Biological Process
proteolysis | establishment of localization | negative regulation of cellular process | response to misfolded protein | intracellular transport | cellular process | protein K63-linked ubiquitination | organic substance catabolic process | localization | proteolysis involved in cellular protein catabolic process | negative regulation of signaling | establishment of localization in cell | cytosolic transport | regulation of cellular process | catabolic process | response to topologically incorrect protein | negative regulation of epidermal growth factor receptor signaling pathway | cellular response to topologically incorrect protein | response to stimulus | endosomal transport | response to stress | regulation of cell proliferation | cellular protein catabolic process | cellular localization | proteasomal protein catabolic process | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | protein modification process | macromolecule modification | nitrogen compound metabolic process | regulation of signal transduction | protein monoubiquitination | cellular response to stress | protein catabolic process | protein modification by small protein conjugation | vesicle-mediated transport | ubiquitin protein ligase activity | proteasome-mediated ubiquitin-dependent protein catabolic process | protein polyubiquitination | protein metabolic process | response to organic substance | protein ubiquitination | cellular macromolecule catabolic process | metabolic process | ubiquitin-protein transferase activity | protein quality control for misfolded or incompletely synthesized proteins | negative regulation of ERBB signaling pathway | organic substance metabolic process | regulation of epidermal growth factor receptor signaling pathway | protein modification by small protein conjugation or removal | retrograde transport, endosome to Golgi | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of signal transduction | regulation of ERBB signaling pathway | cellular protein metabolic process | cellular protein modification process | protein K48-linked ubiquitination | cytoplasm protein quality control by the ubiquitin-proteasome system | cellular response to misfolded protein | cellular metabolic process | cellular response to organic substance | modification-dependent protein catabolic process | regulation of signaling | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
