QuickView for RPL23A (gene)

Gene Symbol:

RPL23A Homo sapiens

Full name:

ribosomal protein L23a

Synonyms:

L23A, MDA20, 60S ribosomal protein L23a, large ribosomal subunit protein uL23, melanoma differentiation-associated gene 20

Genomic Location:

Chr 17: 24071127-24075501

Description:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L23P family of ribosoma...

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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L23P family of ribosomal proteins. It is located in the cytoplasm. The protein may be one of the target molecules involved in mediating growth inhibition by interferon. In yeast, the corresponding protein binds to a specific site on the 26S rRNA. This gene is co-transcribed with the U42A, U42B, U101A, and U101B small nucleolar RNA genes, which are located in its third, first, second, and fourth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  TGANTCA_AP1_C ,  TGGNNNNNNKCCAR_UNKNOWN ,  CTTTGA_LEF1_Q2 ,  TCF4_Q5 ,  AP1_Q6_01 ,  LEF1_Q6 ,  BACH2_01 ,  AACYNNNNTTCCS_UNKNOWN ,  AP1_Q2_01 ,  HMGIY_Q6 ,  BACH1_01 ,  ATF1_Q6 ,  CREL_01

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Cytogenetic Map:

17q11.2

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