QuickView for RPL41;jsessionid=0A2D14162E0F5D39CFF9A1C4B471CDC3 (gene)

Gene Symbol:

RPL41 Homo sapiens

Full name:

ribosomal protein L41

Synonyms:

L41, 60S ribosomal protein L41, HG12 protein, homologue of yeast ribosomal protein YL41, large ribosomal subunit protein eL41

Genomic Location:

Chr 12: 54796641-54797883

Description:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with...

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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with the yeast ribosomal protein YL41, belongs to the L41E family of ribosomal proteins. It is located in the cytoplasm. The protein can interact with the beta subunit of protein kinase CKII and can stimulate the phosphorylation of DNA topoisomerase II-alpha by CKII. Two alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  ETS_Q4 ,  CREBP1CJUN_01 ,  CREB_Q4_01 ,  RYTTCCTG_ETS2_B ,  ZF5_01 ,  YGACNNYACAR_UNKNOWN ,  CREB_Q4 ,  WHN_B ,  GGGAGGRR_MAZ_Q6 ,  TGAYRTCA_ATF3_Q6 ,  CREBP1_Q2 ,  DBP_Q6 ,  GTGACGY_E4F1_Q6 ,  GGCNRNWCTTYS_UNKNOWN ,  YTTCCNNNGGAMR_UNKNOWN ,  E4F1_Q6 ,  MGGAAGTG_GABP_B ,  AP2_Q3 ,  WCTCNATGGY_UNKNOWN ,  CREB_Q2 ,  CP2_02 ,  TGACGTCA_ATF3_Q6 ,  CTTTGT_LEF1_Q2 ,  GCTNWTTGK_UNKNOWN ,  CREB_01 ,  CP2_01

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Cytogenetic Map:

12q13.2

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